The paper is: S E P Smith et al, Maternal immune activation alters fetal brain development through interleukin-6. From the International Society for Infectious Diseases. Importantly, the work does not simply mimic the gecko foot, but builds on it, to develop a material suitable for the intended use. As you read the item, note that they are not making synthetic gecko feet, but rather using some of what they learned about gecko feet to help them design a new material. * Synthetic bacterial genome (1/24/08). His family reports that he has a long history of . Yet measles remains a major killer. Just search on larch. The active drug is attached to a large molecule called a dendrimer. Here is a campus news story on the funding of this project by the Gates Foundation: "QB3 + Gates' millions = a cure? There is also a government report on the incident. Similarly, synthetic small RNA molecules may be useful to biologists to probe gene function -- and may be useful as therapeutic agents. The paper: A A McCormick et al, Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: Safety and immunogenicity in a phase I clinical study. The traditional method of screening for cervical cancer is the pap smear, which looks for abnormal cells; in poor countries, little or no screening may be done. Cancer Quest, a broad informational resource, largely organized as a tutorial, from G Orloff, Emory Univ. An important characteristic of this cancer is that each case expresses a unique antigen, reflecting its development from a single immune system cell. So this work may give us one more piece of a complex puzzle. Berkeley Science Review, issue 12, p 12, Spring 2007. The Scientist for Sept 13, 2004 (Vol 18 #17) has the feature topic of RNAi, with multiple articles: classic.the-scientist.com/2004/9/13/. Accompanying news story: E M Cantin & J J Rossi, Molecular medicine: Entry granted. A short summary is that they found no evidence of vaccine-induced problems, but they also note areas where the evidence is insufficient to reach a conclusion and further study is needed. Harvard Univ Press, 2003. All are freely available online. This item is listed on this page for HIV and HPV. The economics of vaccine production are complex, and in some cases not very good. One important general point from the story is the problem of knowing what long term effects of a treatment are, especially the smaller effects -- without doing long term studies with large numbers of patients. Enjoy the story, and Guarante's enthusiasm. Their view is not entirely accepted at this point. This set seems to be freely available. He discusses evidence that it may be, though conclusive evidence is not yet available. They are not yet big successes; perhaps that will take time, or perhaps there is less here of commercial importance than we would like to believe. Anfinsen shared the 1972 Nobel prize for Chemistry "for his work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation". The report addresses numerous possible side effects of vaccines, and tries to analyze whether evidence supports a causal relationship between vaccine and effect. It broadly deals with issues arising from reproductive and genetic technologies, and includes interactive questions which you can try to evaluate for yourself. Freely available at http://www.nejm.org/doi/full/10.1056/NEJMe0901167. Microbe, the news magazine of the American Society for Microbiology, is free online; this item is at forms.asm.org/microbe/index.asp?bid=42381. http://www.newscientist.com/article/mg19526114.000. A news story on vaccine development. The paper is accompanied by a "perspective" article: C B Saper, Biomedicine: Life, the universe, and body temperature. 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